Staphylococcus aureus - Xen31 | PerkinElmer

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Staphylococcus aureus - Xen31

Staphylococcus aureus - Xen31 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from a parental strain from the American Type Culture Collection, used under license. Staph. aureus-Xen31 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

部件号 119242
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幸运8平台彩票 For laboratory use only. This product is intended for animal research only and not for use in humans.

详情 信息

幸运8平台彩票Infectious disease is a perennially important area for both life science research and drug discovery. Some of the first applications of IVIS® imaging technology were in tracking infections and monitoring host responses, and these applications are still at the forefront of research. PerkinElmer's bioluminescent infectious disease light-producing microorganisms have been developed to mimic both acute and chronic standard infection protocols presently used by researchers.

  • Engineered Bacterium: Staphylococcus aureus - Xen31
  • Parental Strain: American Type Culture Collection, used under license
  • In Vitro/Ex Vivo: Growth and Antibiogram profiles, Biofilm
  • In Vivo: Sepsis, Soft tissue, and Biofilm models

Advantages of using bioluminescent light-producing microorganisms for drug discovery in vitro:

  • Rapid and readily amenable to high throughput screening, e.g., 96 or 384-well format
  • Sensitivity - subtle changes in cellular viability are rapidly detected
  • Inexpensive - no additional substrates needed for bacterial assays

Advantages of using bioluminescent light-producing microorganisms for drug discovery in vivo:

  • Rapid identification of lead drug candidates
  • Real-time efficacy data
  • May help to decrease drug failure by allowing disease relapse to be monitored in the same animal

规格

革兰氏阳性革兰氏阴性 Gram positive
荧光素酶分类 Bacterial luciferase
光学成像分类 Bioluminescence Imaging
产品品牌名称 XenoLight
运输条件 环境
治疗领域 Bacterial infection
产品尺寸 1 agar plate
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