L-proline, uniformly labeled with C-14. 14C-L-proline is commonly used in proline metabolism, amino acid uptake and release, and protein synthesis studies.
Application of [14C]Proline can be found in: dual proline labeling protocol for individual “baseline” and “response” biosynthesis measurements in human articular cartilage, inhibitory effect of vitamin E on proinflammatory cytokines-and endotoxin-induced NO release in alveolar macrophages, the biomechanics of embryonic tendon and evidence that the development of mechanical properties depends on the actinomyosin machinery, axonal release of glutamate analog and l-14C-proline from segments of sciatic nerve following electrical and magnetic stimulation, etc.
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This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.
幸运8平台彩票This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.
The use of substances labeled with carbon-14 has been extraordinarily valuable in many aspects of the life sciences for over half a century. One of the most versatile and simple ways to install carbon-14 in many compounds of interest is by methylating available heteroatoms like nitrogen, oxygen and sulfur to afford corresponding methyl-14C analogues.