Flexar UHPLC | HPLC and UHPLC Pumps | PerkinElmer


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Flexar UHPLC

在进行较高难度的分析应用时,当您需要在短时间里获得更多的数据,Flexar UHPLC是一个完美的选择。Flexar UHPLC主要用来检测高通量样品,具备高灵敏度和分离度,超乎寻常的流量精准度和快速分析等特点。

部件号 N2910535

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详情 信息

超高性能意味着最高的分离度、最高的灵敏度和最快的分析速度,换句话说,就是一个顶级的液相色谱系统。Flexar FX-20就是顶级的超高效液相色谱仪,拥有最大的通量,但最小的财务压力。在更短的时间里获得更多的样品信息, 提升您的工作效率。这正是您需要的产品。 色谱软件部分,您也可以选择Chromera CDS或是Totalchrom,利用强大的、易于使用的Chromera控制和数据处理软件,您会得到比以往都大的配置范围,更好的满足实验室的需求。Flexar UHPLC可以提供的最大流速到5mL/min,耐压超过18,000 psi。另外还配备了高速的自动进样器、柱温箱和检测器。PDA检测器可以提供行业中最快的采集速率。


型号名称 FX-20 Pump


System Components
Description Part Number


FX-20 Pump




UHPLC Autosampler




幸运8平台彩票Standard Column Oven

Peltier Column Oven





幸运8平台彩票FX-UV/Vis Detector

幸运8平台彩票PDA Plus Detector




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QSight Triple Quadrupole LC/MS/MS

Whether you’re a lab manager or a bench chemist, you know firsthand how things are changing quickly in food and environmental analysis. And your lab needs to change to keep pace.



A Robust Method for the Analysis of Commonly Used Sunscreen Compounds for Compliance with New FDA Regulations

幸运8平台彩票Over time, exposure to ultra violet (UV) ,radiation from the sun or tanning beds can ,damage the skin’s cellular DNA, resulting in ,mutations that cause 3.5 million cases of skin ,cancers and about 11,500 deaths in the U.S. ,each year, for a total cost of nearly $2 billion. ,There are three types of UV: UVC, UVB, and ,UVA.

Analysis of Biocides with the PerkinElmer Flexar FX-15 UHPLC System Equipped with a PDA Detector

幸运8平台彩票Biocides are chemical substances that are used to kill or inhibit harmful organisms. Biocides have a wide range of applications in consumer and industrial products.

PDF 955 KB
Analysis of Chlorophenols in Water by UHPLC with PDA Detection

This application will focus on the solid phase extraction (SPE) and HPLC analysis of chlorophenols in three tap water samples.

PDF 989 KB
Analysis of Common Antioxidants in Edible Oil with the PerkinElmer Flexar FX-15 System Equipped with a PDA Detector

Phenolic antioxidants and ascorbyl palmitate are commonly used in food to prevent the oxidation of oils. Oxidized oils cause foul odor and rancidity in food products.

Analysis of Fat-Soluble Vitamins by UHPLC Using UV Detection

幸运8平台彩票In 2009, the United States Pharmacopeial Convention introduced the USP Dietary Supplements Compendium (DSC) – an industry directed resource featuring regulatory guidance, documents, supplemental information, and reference tools.

Analysis of Ginsenosides in Ginseng Root with the PerkinElmer Flexar FX-15 System Equipped with a PDA Detector

幸运8平台彩票Ginseng has been used as an herbal medicine in Asia for over two thousand years for its purported various health benefits, including antioxidant, anticarcinogenic, antiinflammatory, antihypertensive and anti-diabetic. The pharmacologically active compounds behind the claims of ginseng’s efficacy are ginsenosides; their underlying mechanism of action although not entirely elucidated appears to be similar to that of steroid hormones. There are a number of ginseng species, and each has its own set of ginsenosides.

PDF 511 KB
Analysis of Isoflavones in Soy Products by UHPLC with UV Detection

幸运8平台彩票The goal of this work was to develop a simpler, faster and reliable LC method for the analysis of the six most widely-used isoflavones in soy products.

Analysis of Isoflavones with the PerkinElmer Flexar FX-15 UHPLC System Equipped with a PDA Detector

幸运8平台彩票Foods from plants are complex mixtures of chemicals including both essential nutrients and biologically active non-essential nutrients, referred to as phytochemicals.

PDF 992 KB
Analysis of Patulin in Apple Juice by UHPLC with UV Detection

幸运8平台彩票The focus in this work was to develop a simple, robust, and reliable LC method for the analysis of patulin in apple juice.

Analysis of Vanillin, Ethyl Vanillin, and Coumarin in Vanilla Extract Products by UHPLC with PDA Detection

With the focus on possible vanilla extract adulteration, this application focuses on the HPLC separation and quantitation of vanillin, ethyl vanillin, and coumarin in three store-bought vanilla extracts.

Analysis of the Mycotoxin Patulin in Apple Juice Using the Flexar FX-15 UHPLC-UV

幸运8平台彩票Patulin is produced by various molds, which primarily infect the moldy part of apples. Removing the moldy and damaged parts of the fruit may not eliminate all the patulin because some of it may migrate into sound parts of the flesh.

PDF 913 KB
Cannabinoid Monitoring in Dried Cannabis Flowers

This application describes an analytical method for the chromatographic separation and quantitative monitoring of seven primary cannabinoids, including THC and THC-A, in cannabis extracts by HPLC with PDA detection. Naturally occurring cannabinoids, the main biologically active component of the cannabis plant, form a complex group of closely related compounds, of which 113 are known and 70 are well described. Of these, the primary focus has been on ?9-tetrahydrocannabinol (THC), as the primary active ingredient due to its pharmacological and toxicological characteristics, upon which strict legal limits have been enforced.

Determination of a-acids in Hops and Beers

幸运8平台彩票One essential aspect of the quality control in beer brewing is making sure that the type and

PDF 906 KB
Fast Analysis of Fat-Soluble Vitamins Using Flexar FX-10 and Chromera CDS

Sweeteners are low or zero-calorie sugar substitutes that are added in drinks, processed foods and pharmaceutical products to provide the sweet taste of table sugar, which is also called sucrose.

Quality Control of Drug Substances in Headache Medicines with PerkinElmer Flexar UHPLC System Equipped with a PDA Detector

幸运8平台彩票Acetaminophen and aspirin are the drugs of choice used to relieve the symptoms of common headache. Acetaminophen, which is also called paracetamol, is widely used as a pain reliever (analgesic) and fever reducer (antipyretic). Because of its fast onset (eleven minutes after intake), acetaminophen is very effective. However, every year its misuse (dose exceeding the daily adult limit of four grams) can cause fatal liver damage. This application note presents a modified USP method for the analysis of aspirin, acetaminophen and caffeine using a superficially porous particle column and a PerkinElmer® UHPLC platform.

Quantification of Benzodiazepines in Plasma Using UHPLC Time-of-flight Mass Spectrometry

Presented is an alternative technique to quantitate benzodiazepines in plasma using a rapid protein precipitation method with a fast LC separation method in combination with TOF-MS.

Rapid UHPLC Determination of Common Preservatives in Cosmetic Products

幸运8平台彩票This application note will present a fast, sensitive and reliable UHPLC analysis of six common parabens. A PerkinElmer Flexar FX-15 UHPLC system fitted with a Flexar FX PDA photodiode array detector was used. The separation was achieved using a PerkinElmer Brownlee Analytical C18, 1.9 µm 50 mm x 2.1 mm column.

PDF 960 KB
Rapid UHPLC Determination of Nine Common Herbicides in Drinking Water with the PerkinElmer Flexar FX

Water polluted by herbicides leach and runoff can cause human health problems including cancer tumors, reproduction deformity, disruption of the endocrine system and DNA damage. This application presents a sensitive and robust liquid chromatography method to test nine widely used herbicides (Figure 1), using a 3 µm UHPLC column to achieve very high throughput at a low flow rate to reduce testing time and solvent consumption. The throughput is compared to that of a conventional C18 HPLC column. Method conditions and performance data including precision and linearity, are presented.

PDF 750 KB
Simultaneous Analysis of Nine Food Additives with the PerkinElmer Flexar FX-15 System Equipped with a PDA Detector

This application note presents a fast and robust liquid chromatography method to simultaneously test nine widely used additives. Among the additives tested are: preservatives (benzoic acid, sorbic acid, dehydroacetic acid and methylparaben); artificial sweeteners (acesulfame potassium, saccharin and aspartame); flavoring agent (quinine); and a stimulant (caffeine).

PDF 938 KB
The Analysis of Sunscreen-Active Ingredients and Parabens in Lotions and Lip Balms by UHPLC with PDA Detection

Individuals typically use 5-20 cosmetics per day, many of which contain sunscreen to prevent skin damage from the sun’s radiation, and antimicrobial preservatives called parabens. Although sunscreen-active ingredients are designed to block UV radiation, some cell damage may be caused when these ingredients are illuminated by sunlight after absorption into the skin. For example, oxybenzone, an ingredient considered safe by the FDA (Food and Drug Administration), is believed to contribute to the recent rise in melanoma cases by increasing the production of DNA-attacking free radicals upon UV exposure. Additionally, studies have shown oxybenzone to behave similarly to the hormone estrogen, suggesting that it may also contribute to the development of breast cancer. Parabens are absorbed through the skin via cosmetic applications and can be found in nearly all adult urine samples, with the highest concentrations observed in adult females and adolescents. Furthermore, parabens are thought to have estrogenic activity, which affects the expression of genes regulated by the natural form of estrogen, leading to early puberty in girls and an increased risk for the development of breast cancer.

PDF 890 KB
The Qualitative and Quantitative Analysis of a-Acids in Hops and Beers by UHPLC with UV Detection

Alpha acids (a-acids) are a class of chemical compounds of primary importance in the production of beer. They are found in the resin glands of the flowers of the hop plant (Humulus lupulus) and are normally added to the boil after mashing the grains, providing beers with their aroma and bitter taste. The a-acids found in hop resins are isomerized to form the iso-a-acids during prolonged boiling in the wort. The degree of isomerization and the amount of bitter taste produced by the addition of hops is highly dependent on the type of hop and the length of time the hops are boiled. Longer boil times will result in isomerization of more of the available a-acids, making the beer more bitter. The a-acid percentages vary within specific varieties of hops, depending on the growing conditions, drying methods, age of hops, climate and other factors. Figure 1 shows the common a-acids and iso-a-acids involved in the beer brewing process. Since the quality and quantity of a-acids is so important in consistently providing individual beers with their recognizable taste, it is essential to monitor their amount in hops and beers and to monitor the formation of the iso-a-acids during the beer brewing process. The focus of this application note is to provide an easy, straightforward, and robust analytical method for establishing the type and amount of a-acids in hops pellets, as well as determining the amount of a-acids and iso-a-acids in various beers.





Assessment of Extractables and Leachables Associated with Pharmaceutical Packaging

Extractables and leachables studies are critical for maintaining the quality of your drug product and complying with GMP regulations during drug development and final batch release. Exposure to extractables and leachables could have a detrimental impact on the safety and efficacy of a final drug product. Testing for these contaminants is critical in every part of pharmaceutical packaging including the packaging system used to store drug products.

PDF 881 KB